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Combination of autophagy stimulator AR-12 and cellulose ethers. Survival analysis of FVB mice infected i.c. with RML prions. For combination therapy, the mice were treated with a single subcutaneous injection of either CE-5RW (a, b) or 60SH-50 (c, d) 30 days before prion inoculation. Thirty days after prion inoculation, the mice were treated with AR-12 as above, until the end of the experiment (250 dpi).
