Table 1:

General characteristics of each group at 6 weeks (A, prior to treatment, (n=7/group) and at 14 weeks (B, 8 weeks post-treatment, n=6–7/group).

1A	Normal	CKD	CKD ELP-VEGF

Body weight (kg)	48.3 ± 5.6	49.4 ± 1.7	43.3 ± 3.3
Mean arterial pressure (mm Hg)	101 ± 5.3	128.7 ± 9.8^*	137.7 ± 10.8^*
Renal artery stenosis (%)	0	66.7 ± 2.9^*	70.2 ± 3.6^*
Tissue perfusion (mL/min/cc tissue)	4.4 ± 0.2	3.7 ± 0.2^*	3.3 ± 0.3^*
RVR (mm Hg/mL per min)	0.21 ± 0.03	0.29 ± 0.05^*	0.44 ± 0.03^*
Cortical volume (cc)	198.1 ± 13.3	127.0 ± 6.0^*	145.2 ± 6.9^*
Medullary volume (cc)	62.36 ± 1.7	46.5 ± 2.6^*	44.2 ± 4.4^*

1B	Normal	CKD	CKD ELP-VEGF

Body Weight (kg)	62.3 ± 1.4	68 ± 2.1	62.2 ± 3.9
Mean arterial pressure (mm Hg)	106 ± 2.8	132.1 ± 1.9^*	124.0 ± 4.3^*
Tissue perfusion (mL/min/cm³ tissue)	4.7 ± 0.2	4.1 ± 0.2^*	4.4 ± 0.5^†
RVR (mm Hg/mL per min)	0.11 ± 0.4	0.28 ± 0.02	0.23 ± 0.02^*^†
Cortical volume (cm³)	210.9 ± 6.3	137.7 ± 5.2^*	167.6 ± 15.8^*^†^{^}
Medullary volume (cm³)	57.5 ± 4.8	48.2 ± 3.2^*	55.4 ± 5.1^†^{^}

Values are expressed as mean ± SEM. Renal volume is presented as the sum of cortical or medullary area for both kidneys. RVR: Renal vascular resistance

p < 0.05 vs normal

^†

p < 0.05 vs untreated CKD at 14 weeks

^{^}

p < 0.05 vs 6 weeks (Table 1A).