A 35-year-old male presented with complaints of diminution of vision in OD following intravitreal injection of anti-VEGF 1 month back. He was a known case of Pseuxanthoma Elasticum with angioid streaks and choroidal neovascular membrane (CNVM) and had received 8 intravitreal injections in OD and 10 intravitreal injections in OS. On examination, anterior segment of OD showed rosette cataract with posterior capsule rupture [Fig. 1]. Anterior segment of OS was unremarkable. The patient was advised cataract surgery with IOL implantation for OD.
Figure 1.
Retro-illumination images showing iatrogenic cataract and defect in posterior capsule (arrows, a). Rosette pattern is appreciable in high magnification images (b)
Intravitreal injections have become the most common intraocular procedure worldwide.[1] Common injection related complications include subconjunctival hemorrhage, endophthalmitis, and retinal detachment. Iatrogenic cataract following intravitreal injection has an incidence of 0.44-- 0.6% and is usually attributable to direct injury with the injection needle.[2,3]
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
References
- 1.Jamrozy-Witkowska A, Kowalska K, Jankowska-Lech I, Terelak-Borys B, Nowosielska A, Grabska-Liberek I. Complications of intravitreal injections--own experience. Klin Oczna. 2011;113:127–31. [PubMed] [Google Scholar]
- 2.Ghasemi Falavarjani K, Nguyen QD. Adverse events and complications associated with intravitreal injection of anti-VEGF agents: A review of literature. Eye. 2013;27:787–94. doi: 10.1038/eye.2013.107. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3.Angulo Bocco MC, Glacet-Bernard A, Zourdani A, Coscas G, Soubrane G. Intravitreous injection: Retrospective study on 2028 injections and their side effects. J Fr Ophtalmol. 2008;31:693–8. doi: 10.1016/s0181-5512(08)74383-3. [DOI] [PubMed] [Google Scholar]