Table 1.

Susceptibilities of cell culture lines most commonly used for isolation and detection of waterborne enteric viruses.

Cell Line	ADENO	CV-A	CV-B	ECHO	PV	REO	ROTAV	ASTROV
Human Embryonic Kidney	++	+	+		+	+
A549	++++
Buffalo Green Monkey (BGM)	+	+	++++	++	+++	+++
Human rhabdomyosarcoma	-	++	-	++	++
Caco-2 *	+	+	++	?	+	+	+	+
PLC/PRC/5 **	++		++	++?
HEL-299 ***	++	++	++	-	+
RD	+	++	-	++	+	+

Note: The number of + signs indicate the relative degree of replication of the virus in the specific cell line. A “–“sign indicates no replication. *[23] **[24,25] ***[26] ADENO: Adenovirus; CV-A: Coxsackievirus A; CV-B: Coxsackievirus B; ECHO: Echovirus; PV: Poliovirus; REO: Reovirus, ROTAV: Rotavirus; ASTROV: Astrovirus, RD: Rhabdomyosarcoma titers in cell culture. Thus, it should be recognized that much of our information on viruses in water and the effectiveness of treatment processes comes from a very limited group of enteroviruses. The question mark indicates potential replication of the virus in the corresponding cell line.