Figure 6.

Tumor-specific T cell infiltrates correlate with cytokine production of the TIL product. Pearson’s correlation of the percentage of cytokine production of expanded T cells as defined in Figure 4 with tumor-specific infiltrates of (a) CD4⁺ (left panel) CD8⁺ (right panel) CD3⁺ T cells, (b) PD-L1 expression on tumor cells and on immune cells, (c) CD69⁺/CD103⁺ T cell population within CD4⁺ (left) and CD8⁺ (right) T cells, (d) with CD279^hi CD4⁺ T cells (left panel) and CD8⁺ T cells (right panel), and with (e) with Foxp3⁺/CD25^high CD4⁺ T cells. (** p < .01;*** p < .001. If no indication, p ≥ 0.05).