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. 2019 Jun 29;14(12):1234–1244. doi: 10.1080/15592294.2019.1634988

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Figure 3. — Methylation patterns of MEST, KvDMR1, H19 DMR and P3 promoter IGF2 in placenta samples by bisulfite genomic sequencing. The columns represent the successive CpGs and the rows represent the different clones. Black circles represent methylated CpGs and white circles represent non-methylated CpGs. The graph to the right represents 5-mC (%) ± SEM of each group; ISA – Idiopathic spontaneous abortion. (a) Methylation status of 22 CpGs at MEST in three placenta samples of controls and three placenta samples of idiopathic SA. (b) Methylation status of 24 CpGs at KvDMR1 in three placenta samples of controls and three placenta samples of idiopathic SA. (c) Methylation status of 18 CpGs at H19 DMR in three placenta samples of controls and three placenta samples of idiopathic SA. (d) Methylation status of 33 CpGs at P3 IGF2 in three placenta samples of controls and three placenta samples of idiopathic SA.