Table 1.
SYK candidate substrates with known nuclear localization and transcriptional regulator function.
| Symbol | Entrez Gene Name | Phosphorylation site | SILAC ratio |
|---|---|---|---|
| RUVBL1 | RuvB-like AAA ATPase 1 | Y454 | 0.24 |
| YBX1 | Y box binding protein 1 | Y72, Y158, Y162, Y208 | 0.25 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | Y674 | 0.30 |
| TDRD3 | tudor domain containing 3 | Y283 | 0.31 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88 kDa | Y489 | 0.32 |
| STAT3 | signal transducer and activator of transcription 3 | Y705 | 0.32 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | Y101 | 0.34 |
| BASP1 | brain abundant, membrane attached signal protein 1 | Y12 | 0.39 |
| LSR | lipolysis stimulated lipoprotein receptor | Y328, Y406 | 0.39 |
| EGFR | epidermal growth factor receptor | Y869, Y1110, Y1172, Y1197 | ≥ 0.39 |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 | Y1005, Y877 | 0.47 |