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. 2019 Oct 15;5:56. doi: 10.1038/s41421-019-0125-7

Author Correction: Targeted exon skipping with AAV-mediated split adenine base editors

Jackson Winter 1, Alan Luu 2,3, Michael Gapinske 1, Sony Manandhar 1, Shraddha Shirguppe 1, Wendy S Woods 1, Jun S Song 2,3, Pablo Perez-Pinera 1,3,4,5,
PMCID: PMC6796830  PMID: 31638617

Correction to: Cell Discovery (2019) 5:41

10.1038/s41421-019-0109-7, Published online 20 August 2019

In the original publication of this article1, Fig. 4 was labelled incorrectly. The second panel displaying HSF1 Exon 10 should be labelled as HSF1 Exon 11, while the third panel displaying JUP Exon 11 should be labelled as JUP Exon 10. The same labelling change should be applied to the corresponding panels in Fig. 5, as HSF1 Exon 10 and JUP Exon 11 were incorrectly labelled in that figure as well and should be replaced with HSF1 Exon 11 and JUP Exon 10, respectively.

Fig. 4. Quantification of genomic DNA mutation rates created by several ABE constructs at multiple target sites.

Fig. 4

High-throughput sequencing was used to quantify rates of A > G genomic DNA mutation and rates of exon skipping across multiple targets using several ABE variants. * and ** correspond to P < 0.05 and P < 0.01, respectively by two-tailed unpaired Student’s t test across two biological replicates

Fig. 5. Quantification of exon skipping rates at multiple gene targets induced by several ABE constructs.

Fig. 5

High-throughput sequencing of cDNA was used to quantify rates of exon skipping across multiple targets using several ABE variants. * and ** correspond to P < 0.05 and P < 0.01, respectively by two-tailed unpaired Student’s t test across two biological replicates

All instances of HSF1 exon 10 within the text should be corrected to HSF1 exon 11 and all instances of JUP exon 11 should be corrected to JUP exon 10.

References

  • 1.Winter, J., Luu, A., Gapinske, M., Manandhar, S., Shirguppe, S., Woods, W.S., Song, J.S. & Perez-Pinera, P. Targeted exon skipping with AAV-mediated split adenine base editors. Cell Discov. 5, 41 (2019). [DOI] [PMC free article] [PubMed]

Articles from Cell Discovery are provided here courtesy of Nature Publishing Group

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