Table 1. HCC patients (n = 239) categorized by NLR, PLR and their clinical pathologic characteristics.
Clinical character | NLR | PLR | |||||
---|---|---|---|---|---|---|---|
≤2.92 (n = 135) | >2.92(n = 104) | P-value | ≤128.1(n = 152) | >128(n = 87) | P-value | ||
Age, years | 49.0 ± 12.47 | 51.28 ± 11.33 | 0.34 | 48.82 ± 11.21 | 52.54 ± 13.01 | 0.02 | |
Serum albumin, g/L | 41.36 ± 0.38 | 41.49 ± 0.5 | 0.59 | 41.82 ± 0.39 | 40.97 ± 0.49 | 0.18 | |
Tumor size, cm | 5.01 ± 0.26 | 6.99 ± 0.36 | 0.00 | 5.18 ± 0.25 | 7.17 ± 0.39 | 0.00 | |
Platelet 10ˆ9/L | 156.0 ± 6.92 | 167.7 ± 6.89 | 0.25 | 133.4 ± 4.43 | 209.7 ± 9.03 | 0.00 | |
TBil, µmol/L | 14.2 ± 0.63 | 16.24 ± 1.52 | 0.18 | 14.56 ± 0.57 | 16.02 ± 1.82 | 0.35 | |
ALT, U/L | 41.06 ± 2.77 | 44.91 ± 3.19 | 0.36 | 41.66 ± 2.39 | 44.62 ± 3.95 | 0.49 | |
AST, U/L | 44.51 ± 2.72 | 50.18 ± 3.05 | 0.17 | 44.18 ± 2.14 | 52.28 ± 4.12 | 0.06 | |
PT, s | 13.22 ± 0.10 | 13.33 ± 0.10 | 0.57 | 13.38 ± 0.09 | 13.06 ± 0.09 | 0.02 | |
Gender | Male | 115 | 85 | 0.49 | 132 | 68 | 0.10 |
Female | 20 | 19 | 20 | 19 | |||
HBsAg | Negative | 23 | 14 | 0.48 | 19 | 18 | 0.10 |
Positive | 112 | 90 | 133 | 69 | |||
AFP, ng/mL | ≤20 | 50 | 34 | 0.49 | 45 | 39 | 0.02 |
>20 | 85 | 70 | 107 | 48 | |||
Liver cirrhosis | No | 33 | 32 | 0.31 | 41 | 24 | 0.92 |
Yes | 102 | 72 | 111 | 63 | |||
Tumor encapsulation | No | 96 | 72 | 0.78 | 110 | 58 | 0.37 |
Yes | 39 | 32 | 42 | 29 | |||
Tumor number | Single | 105 | 77 | 0.54 | 119 | 63 | 0.35 |
Multiple | 30 | 27 | 33 | 24 | |||
Satellite nodules | No | 125 | 96 | 0.98 | 146 | 75 | 0.01 |
Yes | 10 | 8 | 6 | 12 | |||
Edmondson grade | I–II | 103 | 83 | 0.53 | 116 | 70 | 0.52 |
III–IV | 32 | 21 | 36 | 17 | |||
BCLC stage | 0 | 11 | 0 | 0.00 | 10 | 1 | 0.04 |
A | 93 | 60 | 101 | 52 | |||
B | 28 | 17 | 27 | 18 | |||
C | 3 | 27 | 14 | 16 | |||
TNM stage | I | 95 | 48 | 0.00 | 102 | 41 | 0.01 |
II | 30 | 19 | 27 | 22 | |||
III | 10 | 37 | 23 | 24 |
Notes.
Characteristics.
- NLR
- neutrophil-to-lymphocyte ratio
- HBsAg
- hepatitis B surface antigen
- AFP
- α-fetoprotein
- TNM
- tumor-node-metastasis
- TBil
- total bilirubin
- PT
- prothrombin time
- CTP
- Child-Turcotte-Pugh
- BCLC stage
- The Barcelona Clinic Liver Cancer staging
- ALT
- glutamic-pyruvic transaminase
- AST
- glutamic oxalacetic transaminase