Table 1. Model Parameters.

Parameter	Description	Value
$\gamma$	Tension	2 pN µm
$ϵ$	Width of phase field	2 µm
$B_S$	Cell area conservation strength	10 pN/µm2
$\xi$	Friction coefficient	10 pN s/µm2
$n$	Hill coefficient of protrusive force	3
$k_a$	Activation rate	10 s-1
$K_a$	Activation threshold	1 µM
$b$	Basal activation rate	0.1 s-1
$A_t$	Total activator concentration	2 µM
$d_1$	Basal degradation rate	1 s-1
$d_2$	Degradation rate from inhibitor	1 µM-1s-1
$c_1$	Inhibitor degradation coeffecient	1
$c_2$	Inhibitor activation coefficient	15
$\tau$	Time scale of negative feedback	10 s
$D_A$	Activator diffusion coefficient	0.5 µm2/s
$D_R$	Inhibitor diffusion coefficient	0.5 µm2/s
$\sigma$	Noise intensity	0.01 µM2/µm2/s
$\mathrm{\Delta }t$	Time step	0.001 s
$n,m$	Space grid size	256,256
$L_{x,y}$	Space size	50,50 µm