Table 2. Characteristics of the animals at the end of the protocol.
BW: body weight. Values are expressed as the mean ± SEM. Group comparisons were made using two-way ANOVA analysis and Holm-Sidak’s pos t-test.
| Parameters | Sham (n = 11) | AR (n = 13) | Sham Ovx (n = 10) | AR Ovx (n = 10) |
|---|---|---|---|---|
| Body weight, g | 428 ± 15 | 418 ± 20 | 368 ± 11§ | 417 ± 14* |
| Tibia, mm | 51 ± 0.2 | 53 ± 0.3* | 50 ± 0.3§ | 50 ± 0.2§ |
| Heart, mg | 963 ± 20 | 1,685 ± 31* | 765 ± 20§ | 1304 ± 25*§ |
| Heart/BW, mg/g | 2.3 ± 0.1 | 4.1 ± 0.2* | 2.1 ± 0.1 | 3.2 ± 0.1*§ |
| Heart/TL, mg/mm | 18.8 ± 0.3 | 31.9 ± 0.6* | 15.4 ± 0.4§ | 26.0 ± 0.5*§ |
| Left ventricle, mg | 735 ± 17 | 1354 ± 25* | 588 ± 13§ | 1,015 ± 25*§ |
| Left atria, mg | 25 ± 3 | 47 ± 3* | 18 ± 2 | 32 ± 2* |
| Lungs, g | 1.7 ± 0.1 | 3.2 ± 0.3* | 2.4 ± 0.2 | 2.2 ± 0.3 |
| Uterus, mg | 59 ± 4 | 59 ± 3 | 9 ± 1§ | 9 ± 1§ |
Notes.
*
p < 0.001 vs the respective sham group.
§
p < 0.05 vs non-Ovx group.