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. 2019 Sep 19;9(23):6797–6808. doi: 10.7150/thno.36375

Figure 6.

Figure 6

in vivo fibrogenic fibroblast targeting near-infrared phototherapy. (A) Schematic of the experimental strategy for estimating the photothermal effect of IR-780 in vivo . (B) Real time thermal images of IR-780 treated wound tissues irradiated with NIR laser. (C) Schematic depicting the timing of IR-780 based photothermal, photodynamic therapy. (D) Wound healing rate with IR-780 +NIR laser treatment.**, P<0.01. (E) HE staining and (F) immunostaining of wound tissues treated with IR-780 + laser for α-SMA. Analysis of (G) the scar area, (H) scar depth, (I) ECM deposition and (J) expression of α-SMA in the healed wound tissues treated with IR-780. Scale bar, 500 µm in (C,H), 100 µm in (D,I, J). Data are mean ± s.d. **, P<0.01.