Table 3.
The five age-related CpG sites
| CpG ID | Gene symbol | Beta 10631 | Beta 10615 | Beta 10643 | Beta 10586 | Delta beta |
|---|---|---|---|---|---|---|
| cg00945507 | SEC61G | 0.27 | 0.28 | 0.33 | 0.69 | 0.39 |
| cg12768605 | LYPD5 | 0.32 | 0.32 | 0.32 | 0.52 | 0.20 |
| cg13854874 | CHAF1B | 0.24 | 0.23 | 0.20 | 0.49 | 0.27 |
| cg22901840 | DIRAS3 | 0.70 | 0.74 | 0.68 | 0.48 | -0.23 |
| cg07770222 | C8orf31 | 0.60 | 0.55 | 0.59 | 0.81 | 0.23 |
Presented are the age-related CpG sites that showed a >20% difference in DNAm levels between the patient with early-onset Alzheimer’s disease (Patient 10586) and the triplets (Patients 10631, 10615 and 10643).