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. 2019 Oct 30;322(20):1977–1986. doi: 10.1001/jama.2019.17274

Figure 1. Recruitment, Randomization, and Patient Flow of the Participants in a Study of the Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism.

Figure 1.

The difference in the number of participants randomized was due to a chance occurrence and, in part, to the failure to stratify randomization by age in the Thyroid Hormone Replacement for Untreated Older Adults With Subclinical Hypothyroidism Trial (TRUST). The 12-month window was defined as between 334 and 397 days after randomization. IEMO indicates Institute for Evidence-Based Medicine in Old Age.