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. 2019 Mar 4;26(2):688–689. doi: 10.1007/s12350-019-01593-3

Correction to: The effect of beta blocker withdrawal on adenosine myocardial perfusion imaging

C Hoffmeister 1,, R Preuss 2, R Weise 2, W Burchert 2, O Lindner 2
PMCID: PMC6828149  PMID: 30830643

Correction to: Journal of Nuclear Cardiology® Volume 21, Number 6;1223–9 10.1007/s12350-014-9952-y

Regrettably the original version of the above article contained errors in Table 2 and wrong values in the text. The corrected table is presented here and the values which have been corrected now appear in bold text.

Page 1223 Abstract

Global MBF showed an increase from 180.2 ± 59.9 to 193.6 ± 60.8 mL minute/100 g (P = .002) after beta blocker withdrawal.

Page 1225

Mean systolic and mean diastolic blood pressure during adenosine were nearly identical (P = .77 and P = .79) with and without beta blocker. Mean heart rate and mean RPP during adenosine significantly increased after beta blocker withdrawal by 15.2% ± 17% (P = 001) and 16.2% ± 23% (P = .004), respectively.

Page 1226

The data are listed in Table 2, lower third. Global MBF showed a significant increase by 7.4% ± 10% (P = .002) after beta blocker withdrawal. The individual data are depicted in Figure 1. All but three patients had a lower global MBF without beta blocker than with. The segmental MBF values (Figure 2) demonstrated a strong correlation over the entire range of perfusion values. The average effect was a slight perfusion shift of about 1015 mL minute-1/100 g in the range of 100-300 mL minute-1/100 g. The mCR under adenosine declined by 8.1% ± 11% (P = .038) and the normalized RPP by 16.2% ± 21% (P = .004) after betablocker discontinuation

Table 2.

Hemodynamic response under adenosine, perfusion, and left-ventricular function

With beta blocker Without beta blocker ( %) P
Heart rate (BPM) 69.7 ± 12.1 80.3 ± 10.9 10.6 15.2 < .001
Systolic blood pressure (mmHg) 117.3 ± 19.9 118.2 ± 19.3 .9 .8 .77
Diastolic blood pressure (mmHg) 55.8 ± 9.9 56.1 ± 8.8 .3 .5 .79
Rate-pressure product 8159.5 ± 1943.0 9487.0 ± 2025.4 1327.5 16.2 .004
EDV (mL) 164.5 ± 36.5 16.6 ± 43.9 1.9 1.1 .59
ESV (mL) 61.8 ± 12.6 62.9 ± 16.0 1.1 1.7 .64
EF (%) 39.4 ± 10.7 40.6 ± 0.3 1.2 3.0 .29
Global myocardial perfusion (mL/minute/100 g) 180.2 ± 59.9 193.6 ± 60.8 13.4 7.4 .002
Minimal coronary resistance (mmHg/(mL/minute/100 g)) 0.49 ± 0.2 0.45 ± 0.2 − .04 − 8.1 .038
Global perfusion related to RPP (mL/minute/100 g) 229.6 ± 96.7 206.0 ± 73.1 − 23.6 − 10.2 .032

Disclosure

Oliver Lindner was supported by Carinopharm.

Contributor Information

C. Hoffmeister, Email: clhoffmei@gmx.de

O. Lindner, Email: OLindner@hdz-nrw.de.


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