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. 2018 Aug 23;38(9):881. doi: 10.1007/s40261-018-0685-6

Correction to: Gadobutrol: A Review in Contrast-Enhanced MRI and MRA

Lesley J Scott 1,
PMCID: PMC6828359  PMID: 30141093

Correction to: Clinical Drug Investigation 2018;38(8):773–784 10.1007/s40261-018-0674-9

Page 774, Table 1, Ligand structure row/gadobenate dimeglumine column: The cell entry in the “Gadobenate dimeglumine” column, which previously read:

“Macrocyclic”

should read:

“Linear”

The corrected Table 1 is:

Table 1.

Key chemical and physiochemical properties of selected gadolinium-based contrast agents

Property Gadobutrol Gadoteridol Gadoterate
meglumine
Gadobenate dimeglumine Gadopentetate dimeglumine
Ligand structure Macrocyclic Macrocyclic Macrocyclic Linear Linear
Charge Non-ionic Non-ionic Ionic Ionic Ionic
Concentration (mol/L) 1 0.5 0.5 0.5 0.5
Osmolality at 37 °C (osmol/kg H2O) 1.6 0.63 1.35 1.97 1.96
Relaxivities r1/r2 in plasma at 37 °C (mmol/L/s) 5.2/6.1 4.1/5.0 3.6/4.3 6.3/9.2 4.1/4.6
Viscosity at 37 °C 4.96 1.3 2.0 5.3 2.9
Thermodynamic complex stability (log Keq) 21.8 23.8 25.8 22.6 22.1

Adapted from Scott [5]

The original article was corrected.


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