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NE microdomains and their association with different genomic regions. Schematic representation of the linkage between centromeres, telomeres, double strand breaks (DSBs) and other genomic loci and INM proteins. DSB repair factories are linked to the NE by the LINC complex and can be moved by cytoplasmic MTs and positioned in close proximity of the SPB. The different elements are depicted as in Figure 1.
