Table 1.

Transcription factors that regulate the majority of the 17 genes identified by text mining. Each of the 17 genes was searched with the TRRUST version 2 (https://www.grnpedia.org/trrust/), TfactS (http://www.tfacts.org/) and Regulatory Circuits database (http://regulatorycircuits.org/). A total of 140 transcription factors were identified and each transcription factor was associated with at least one of the 17 genes (Supplementary Table S3). The transcription factors linked to most of the 17 genes as determined by direct evidence are shown.

Gene	NF-κB1	Rela	STAT3	STAT1	STAT5A	STAT5B	STAT6
C3
CCL2	√	√	√	√
CRP	√	√	√
CXCL8	√	√	√	√			√
FAS	√	√	√	√
HMOX1	√	√	√	√
ICAM1	√	√	√	√
IGF1			√		√	√
IL6	√	√	√	√	√
IL18	√	√
PPARG	√			√		√
TGFB1	√		√
TNF	√	√	√		√	√
TRAF1	√	√
LEP			√
IL4	√	√					√
IFN-G	√	√	√	√	√	√