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. 2019 Oct 14;24(20):3694. doi: 10.3390/molecules24203694

Table 4.

Representative non-covalent and regioselective (C-R+) DNA-protein conjugation methods.

C-R+ (Non Covalent/Regioselective Methods)
DNA Protein DNA-Protein Conjugate
biotin/monoavidin [54]
graphic file with name molecules-24-03694-i046.jpg graphic file with name molecules-24-03694-i047.jpg graphic file with name molecules-24-03694-i048.jpg
NTA/6His tag/Ni2+ [55]
graphic file with name molecules-24-03694-i049.jpg graphic file with name molecules-24-03694-i050.jpg graphic file with name molecules-24-03694-i051.jpg
DNA aptamer/protein [56]
graphic file with name molecules-24-03694-i052.jpg graphic file with name molecules-24-03694-i053.jpg graphic file with name molecules-24-03694-i054.jpg
peptide ligand/protein [47]
graphic file with name molecules-24-03694-i055.jpg graphic file with name molecules-24-03694-i056.jpg graphic file with name molecules-24-03694-i057.jpg
antigen/antibody-protein [57]
graphic file with name molecules-24-03694-i058.jpg graphic file with name molecules-24-03694-i059.jpg graphic file with name molecules-24-03694-i060.jpg
cofactor/apoenzyme [58,59]
graphic file with name molecules-24-03694-i061.jpg graphic file with name molecules-24-03694-i062.jpg graphic file with name molecules-24-03694-i063.jpg
DNA binding protein [60]
graphic file with name molecules-24-03694-i064.jpg graphic file with name molecules-24-03694-i065.jpg graphic file with name molecules-24-03694-i066.jpg