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. 2019 Nov 6;17:89. doi: 10.1186/s12958-019-0532-5

Correction to: Endometrium metabolomic profiling reveals potential biomarkers for diagnosis of endometriosis at minimal-mild stages

Jingjie Li 1,#, Lihuan Guan 2,#, Huizhen Zhang 2, Yue Gao 2, Jiahong Sun 2, Xiao Gong 4, Dongshun Li 2, Pan Chen 3, Xiaoyan Liang 1, Min Huang 2, Huichang Bi 2,
PMCID: PMC6833161  PMID: 31690315

Correction to: Reprod Biol Endocrinol (2018) 16:42

https://doi.org/10.1186/s12958-018-0360-z

The authors regret that the incorrect identification of “omega-3 arachidonic acid” published in the original manuscript [1]. This classification is incorrect as arachidonic acid is an omega-6 polyunsaturated fatty acid. From a mechanistic standpoint, this mistake might have significance, as arachidonic acid is hypothesized to play a role in inflammatory processes. We have carefully double-checked our original data and compared the fragmentation spectra and m/z referring to Metlin Database again. We are sure that the metabolite should be arachidonic acid, instead of omega-3 arachidonic acid. Given that this misclassification is made in several places within the article’s abstract and text, a correction is warranted.

Accordingly, the name “omega-3 arachidonic acid” mentioned in the following parts should be corrected as “arachidonic acid”:

  • In the results section of Abstract: “The eutopic endometrium metabolomic profile of the endometriosis patients was characterized by a significant increase in the concentration of hypoxanthine, L-arginine, L-tyrosine, leucine, lysine, inosine, omega-3 arachidonic acid, guanosine……”.

  • In the last paragraph of Introduction: “The eutopic endometrium metabolomic profile of endometriosis patients was characterized by a significant increase in the concentration of hypoxanthine, L-arginine, L-tyrosine, leucine, lysine, inosine, omega-3 arachidonic acid, guanosine……”.

  • In the first paragraph of the section with the subheading “Identification of detected metabolites” of Results: “Obviously, levels of hypoxanthine, L-arginine, L-tyrosine, leucine, lysine, inosine, omega-3 arachidonic acid, guanosine…..”

  • In the first paragraph of Discussion: “In this regard, 11 metabolites including hypoxanthine, L-arginine, L-tyrosine, leucine, lysine, inosine, omega-3 arachidonic acid, guanosine……”

  • Figure 2D, “Omega-3 Arachidonic acid”

  • In the third row of Figure 3, “omega-3 arachidonic acid”

  • In the third graph in the first row of Figure 4, “Omega-3 Arachidonic acid”

  • In the 4th row of RPLC mode in Table 2, “Omega-3 Arachidonic acid”

The authors would like to apologize for any inconvenience caused.

Footnotes

The original article can be found online at 10.1186/s12958-018-0360-z

Jingjie Li and Lihuan Guan contributed equally to this work.

Reference

  • 1.Li J, et al. Endometrium metabolomic profiling reveals potential biomarkers for diagnosis of endometriosis at minimal-mild stages. Reprod Biol Endocrinol. 2018;16:42. doi: 10.1186/s12958-018-0360-z. [DOI] [PMC free article] [PubMed] [Google Scholar]

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