Table 7.

Effect of AHR on lipid metabolism related gene levels in epididymal adipose tissue of HFD-induced obese mice.

Gene Function	Name	Fold Change
		AHR100 * vs. HFD	p-Value	AHR500 ** vs. HFD	p-Value
Cholesterol efflux	ABCA1	−1.13	0.152	−1.00	0.978
Regulates the metabolism of lipid and glucose	Adiponectin	−1.02	0.870	1.21	0.217
Imports fatty acids	CD36	1.08	0.664	1.14	0.468
Induction of adipogenesis	CEBP-α	−1.10	0.515	1.23	0.178
Adipocyte differentiation	PPAR-γ	1.19	0.415	1.79	0.023
Fatty acid β-oxidation	CPT1-β	−1.06	0.666	1.02	0.914
	FABP4	−1.08	0.500	1.13	0.312
	PPAR-α	−1.02	0.912	1.55	0.073
Glucose transporter	GLUT4	−1.01	0.934	1.31	0.161
TG lipolysis	HSL	1.03	0.894	1.62	0.031
	LPL	1.16	0.291	1.44	0.028
	ATGL	1.08	0.813	1.78	0.094
Regulate appetite	Leptin	1.31	0.259	−1.38	0.176
Adipocyte lipolysis	Perilipin	1.05	0.814	1.53	0.056
Lipogenesis	SCD1	1.04	0.873	1.70	0.067
	SREBP-1c	1.02	0.911	1.18	0.325
	PDH	−1.05	0.774	1.27	0.085
	DGAT	1.05	0.774	1.61	0.045
	FASN	1.44	0.084	1.54	0.145
House keeping	β-actin	1		1

ABCA1: ATP-binding cassette subfamily A member 1, ATGL: Adipose triglyceride lipase, CD36: Cluster of differentiation 36, CEBP-α; CCAT/enhancer-binding protein, CPT1-β: Carnitine palmitoyltransferase 1, DGAT: Diacylglycerol acyltransferases, FABP4: Fatty acid-binding protein, FASN: Fatty acid synthase, GLUT4: Glucose transporter type 4, HSL: Hormone-sensitive lipase, LPL: Lipoprotein lipase, PDH: Pyruvate dehydrogenase, PPAR-α: Peroxisome proliferator-activated receptor, SCD1: Stearoyl-CoA desaturase-1, SREBP-1: Sterol regulatory element-binding transcription factor. * AHR100: HFD + 100mg/kg B.W. water extract of Allium hookeri root. ** AHR500: HFD + 500mg/kg B.W. water extract of Allium hookeri root.