Table 2. Values of KMAPP and imaxAPP for the four MtCDH variants extracted by fitting the DET and MET data in Figures 10 and 12, respectively, with Equation (2).
CDH variant | DET | MET | ||||
---|---|---|---|---|---|---|
imaxAPP (µA) | KMAPP (mM) | imaxAPP/KMAPP (µA/mM) | imaxAPP (µA) | KMAPP (mM) | imaxAPP/KMAPP (µA/mM) | |
E501C | 1.037 ± 0.007 | 24.0 ± 0.5 | 0.043 ± 0.001 | 13.5 ± 0.3 | 75 ± 4 | 0.180 ± 0.014 |
E653C | 1.39 ± 0.02 | 33 ± 1 | 0.042 ± 0.002 | 20.1 ± 0.3 | 101 ± 3 | 0.199 ± 0.009 |
T680C | 1.025 ± 0.007 | 21.0 ± 0.4 | 0.049 ± 0.001 | 14.2 ± 0.6 | 80 ± 7 | 0.178 ± 0.023 |
D792C | 1.17 ± 0.01 | 18.7 ± 0.5 | 0.063 ± 0.002 | 13.8 ± 0.5 | 85 ± 7 | 0.162 ± 0.019 |