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. Author manuscript; available in PMC: 2020 Apr 23.
Published in final edited form as: Nature. 2019 Oct 23;574(7779):549–552. doi: 10.1038/s41586-019-1662-9

Extended Data Figure 7. LPS-based phage resistance also affects in vivo virulence.

Extended Data Figure 7

Time to death (given as the median ± one standard error) for Galleria mellonella larvae infected with PA14 clones that evolved phage resistance through LPS modification, compared to the phage-sensitive ancestral (n = 209 biologically independent samples). Cox proportional hazards model with Tukey contrasts: Sensitive (ancestral) v LPS ; z = 4.81, p = 1.49 × 10-6. Overall model fit; LRT3 = 44.94, p = 1 × 10-9