Fig. 2.

Clinical values of circPICALM in BC.

a. Relative expression of circPICALM in 40 paired primary BC (T) and adjacent normal (N) tissues, measured by RT-PCR. b. Relative expression of PICALM mRNA in 40 paired primary BC (T) and adjacent normal (N) tissues, measured by RT-PCR. c. The correlation between circPICALM and PICALM expression in 40 BC samples. d. The Kaplan-Meier survival curve comparing patients' survival percentages with relatively high or low expression of circPICALM. e-g. Relative abundance of circPICALM in BC patients compared by LN status, T stage, and grade. (a, b, Paired, two-tailed, Wilcoxon rank-sum test; c. Spearman's rank correlation; d, Log-rank test; e-g, Mann-Whitney U test. **P<0.01).