Figure 5.

Transcranial PBM mitigates MPTP-induced vascular leakage in the SNc. Top and bottom left panels: Representative thresholded images of FITC-LA labelling in the SNc of mice injected with MPTP and exposed to daily PBM treatment (MPTP PBM) or sham treatment (MPTP Sham), as well as saline-injected controls (Saline). Scale bar in the top left image applies to all images. Bottom right panel: Quantification of the percentage of pixels above threshold, as determined from thresholded FITC-LA images. Data are presented as mean ± SEM (n = 8 for Saline, n = 6 for MPTP Sham, n = 6 for MPTP PBM). * p < 0.0001 vs. Saline; ^ p < 0.0001 vs MPTP Sham. Blue dot represents the unshaved mouse.