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. 2019 Nov 11;21(Suppl 6):vi137. doi: 10.1093/neuonc/noz175.574

INNV-33. BARRIERS TO ACCRUAL AND ENROLLMENT IN BRAIN TUMOR TRIALS

Eudocia Lee 1, Ugonma Chukwueke 1, Shawn Hervey-Jumper 2, John DeGroot 3, Pablo Leone 1, Terri Armstrong 5, Susan Chang 6, David Arons 7, Kathy Oliver 8, Kay Verble 9, Al Musella 10, Nicole Willmarth 11, Brian Alexander 1, Amanda Bates 7, Lisa Doherty 1, Evanthia Galanis 12, Sarah Gaffey 1, Thomas Halkin 7, Bret Friday 13, Maryam Fouladi 14, Nancy Lin 1, David Macdonald 15, Minesh Mehta 16, Marta Penas-Prado 5, Michael Vogelbaum 17, Solmaz Sahebjam 17, David Sandak 18, Martin van den Bent 19, Michael Weller 20, David Reardon 1, Patrick Wen 1
PMCID: PMC6847720

Abstract

BACKGROUND

A major impediment to improving neuro-oncology outcomes is poor clinical trial accrual.

METHODS

We convened a multi-stakeholder group including Society for Neuro-Oncology, Response Assessment in Neuro-Oncology, patient advocacy groups, clinical trial cooperative groups, and other partners to determine how we can improve trial accrual.

RESULTS

We described selected factors contributing to poor trial accrual and possible solutions. We focused on patient and community factors, disparities, physician and provider factors, clinical trial factors, and site and organizational factors

CONCLUSIONS

We will implement strategies with the intent to double accrual to neuro-oncology trials over the next 5 years.


Articles from Neuro-Oncology are provided here courtesy of Society for Neuro-Oncology and Oxford University Press

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