Skip to main content
. 2019 May 28;70(4):1377–1391. doi: 10.1002/hep.30651

Figure 3.

Figure 3

Bioreactor‐cultured fibrotic rat liver slices can be maintained for 6 days. (A) Graph shows hydroxyproline (μg/g of liver tissue) in bioreactor‐cultured fPCLSs. (B‐D) mRNA expression of Col1A1, αSMA, and TIMP1 in bioreactor‐cultured fPCLSs at t = 0 and 2‐, 3‐, 4‐, and 6‐day culture. Data are mean ± SEM in n = 5 independent slice experiments. (E) Representative images of αSMA and picrosirius red–stained rat fPCLS at t = 0 and 2, 3, 4, and 6 days in culture. Scale bars = 200 µm. *P < 0.05; **P < 0.01. Abbreviation: IHC, immunohistochemistry.