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. 2019 Oct 31;24(21):3942. doi: 10.3390/molecules24213942

Table 6.

Compounds from fungi and their inclusion within the defined chemical spaces.

Overall Lead-Like Space Drug-Like Space Known Drug Space
Molecular weight (g mol−1) 25.0% 90.6% 96.9%
Lipophilicity (Log P) 78.1% 78.1% 100.0%
Hydrogen bond donors 100.0% 100.0% 100.0%
Hydrogen bond acceptors 3.1% 84.4% 100.0%
Polar surface area (Å2) 3.1% 87.5% 93.8%
Rotatable bonds 62.5% 100.0% 100.0%
All criteria 0.0% 81.3% 90.6%