Table 6.
Overall | Lead-Like Space | Drug-Like Space | Known Drug Space |
---|---|---|---|
Molecular weight (g mol−1) | 25.0% | 90.6% | 96.9% |
Lipophilicity (Log P) | 78.1% | 78.1% | 100.0% |
Hydrogen bond donors | 100.0% | 100.0% | 100.0% |
Hydrogen bond acceptors | 3.1% | 84.4% | 100.0% |
Polar surface area (Å2) | 3.1% | 87.5% | 93.8% |
Rotatable bonds | 62.5% | 100.0% | 100.0% |
All criteria | 0.0% | 81.3% | 90.6% |