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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Nature. 2019 May 1;570(7761):332–337. doi: 10.1038/s41586-019-1195-2

Extended Data Fig. 3 |. Consistency of cells of the same type across individuals.

Extended Data Fig. 3 |

a, Known cell-type marker gene expression for each cell-type. b, Expression of known cell-type marker genes in each cluster (left) and fraction of cells in each cluster expressing each marker gene (right). Vertical blue line represents a scale bar referencing 0.5. c, over-representation analysis (hypergeometric test) within each of the pre-cluster marker sets (rows) of genes identified as markers in Lake et al. 2018 (n=1729 total genes, columns, left) and genes identified as markers of cortical layers in He et al. 2017 (n=3400 total genes, columns, right). d, fraction of cells of each type isolated across all (n=48, left), no-pathology (n=24, center), and AD-pathology (n=24, right) individuals. e, fraction of cells of each type isolated from each individual (n=48, columns).