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. 2019 Oct 23;6(5):ENEURO.0193-19.2019. doi: 10.1523/ENEURO.0193-19.2019

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Copyright © 2019 Kuljis et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 2. — FAPpost synaptic localization does not alter mEPSC and mIPSC properties. A, Example voltage-clamp traces from an untransfected (black) and neighboring FAPpost-expressing (red) L2/3 Pyr cell showing mEPSCs. B, Comparison of mean mEPSC frequency (ANOVA_Frequency: F_(1,16) = 0.2, p = 0.6) and amplitude (ANOVA_Amplitude: F_(1,16) = 0.1, p = 0.8) indicate no difference. C, Cumulative distribution histogram of mEPSC amplitudes (Kolmogorov–Smirnov test, D = 0.05, p = 0.16). D, Example voltage-clamp traces from an untransfected (black) and neighboring FAPpost-expressing (red) L2/3 Pyr cell showing mIPSCs. E, Mean mIPSCs frequency (left) of untransfected and dTom cells were not significantly different (ANOVA_Frequency: F_(1,18) = 0.6, p = 0.4). Mean mIPSC amplitude (right) of untransfected and dTom cells were not significantly different (ANOVA_Amplitude: F_(1,18) = 0.5, p = 0.5). F, Cumulative distribution histogram of mIPSC amplitudes shows a small but significant shift in dTom mIPSC amplitudes (Kolmogorov–Smirnov test, D = 0.15, *p < 0.0001); n = 8–11 cells, N = 7 animals.