The article by Maestrini et al. entitled “Plasma Oxytocin Concentration in Pre- and Postmenopausal Women: Its Relationship with Obesity, Body Composition and Metabolic Variables” [Obes Facts. 2018;11(5):429–439, DOI: 10.1159/000492001] was published with serious errors. Wrong versions of Figures 1 and 2 as well as of Table 2 were given. Ameliorated images of Figures 1 and 2 as well as of Table 2 are presented here.
Fig. 1.
Plasma oxytocin levels in pre-menopausal and post-menopausal normal weight (Pre-NW and Post-NW, respectively) and obese (Pre-OB and Post-OB, respectively) women. Results are expressed as mean ±SD.
Fig. 2.
Relationship between oxytocin percent fat mass (FM, panel A), leptin (panel B) and adiponectin (panel C). Open circles, control group; closed circles, obese group.
Table 2.
Baseline hormone and metabolic characteristics in normal weight (NW) and obese (OB) subjects as whole study group and after stratification in the pre-menopausal (pre) and post-menopausal (post) subpopulations
| Parameters | Normal weight women (n = 53) |
Obese women (n = 56) |
||||||
|---|---|---|---|---|---|---|---|---|
| whole | menopause status |
whole | menopause status |
|||||
| pre (n = 27) | post (n = 26) | p | pre (n = 28) | post(n = 28) | p | |||
| Oxytocin, pg/mL | 2.03±2.09 | 3.5±2.1 | 2.3±1.9 | <0.05 | 0.85±1.22§ | 1.31±1.5§ | 0.4±0.6§ | 0.005 |
| Leptin, ng/mL | 19±11.5 | 21.5±11.7 | 16.5±10.9 | ns | 77.10±25.8§ | 75.5±21.8§ | 78.8±29.7§ | Ns |
| Adiponectin,µg/mL | 19.6±9.5 | 17.4±9.0 | 21.8±9.7 | ns | 9.6±4.5§ | 8.11±3§ | 11.2±5.3§ | 0.01 |
| Glucose, mg/dL | 88.2±10.2 | 88.59±11.5 | 87.88±8.8 | ns | 106.9±25.5§ | 102±16* | 111.9±32* | Ns |
| Insulin, mU/L | 7.7±4.3 | 8.3±4.8 | 7.1±3.7 | ns | 14.4±8.4§ | 14.8±8.4* | 14.1±8.5* | Ns |
| HOMA-IR | 1.71±1.1 | 1.86±1.3 | 1.56±0.88 | ns | 3.82±2.3§ | 3.8±2.4§ | 3.8±2.3§ | Ns |
| HbAlc, % | 5.35±0.25 | 5.34±0.26 | 5.37±0.24 | ns | 6.26±1.03§ | 6.1±0.5§ | 6.5±1.4§ | Ns |
| TC, mg/dL | 210±35 | 206±37 | 214±29.7 | ns | 205±38 | 211±39.6 | 199±37.6 | Ns |
| HDL-C, mg/dL | 68±171 | 65±16.5 | 71.7±17.4 | ns | 41.7±8.8§ | 41±9.3§ | 42.5±8.4§ | Ns |
| LDL-C, mg/dL | 130.7±31.8 | 130.6±34.7 | 131±29.4 | ns | 132.5±35.5 | 139.2±36.1 | 126±34.3 | Ns |
| TGL, mg/dL | 92.3±43.2 | 90.7±46 | 94±41 | ns | 150.5±61.7§ | 151.5±69.8§ | 149.7±54* | Ns |
| FSH, U/L | 54.8±43.7 | 21.48±30.5 | 89.5±23.9 | <0.001 | 26.5±25.6§ | 6.5±5.4* | 45.7±22.3§ | <0.001 |
| LH, U/L | 28.6±20.5 | 14.1±14.9 | 43.8±13.1 | <0.001 | 16.1±13.4§ | 5.04±4.3* | 25.9±10.7§ | <0.001 |
| PRL,µg/L | 14.7±8.7 | 18.2±10.2 | 11.2±4.9 | 0.003 | 17.5±10.8 | 21.5±11.3 | 13.4±8.8 | 0.005 |
| E2, ng/L | 66.5±58.2 | 101.4±62.9 | 28.9±8.1 | <0.001 | 76.8±67.5 | 110.2±80 | 40.2±12.3§ | <0.001 |
| Testosterone, nmol/L | 0.8±0.3 | 0.8±0.2 | 0.9±0.5 | ns | 1.2±0.6§ | 1.1±0.5* | 1.2±0.6 | ns |
Results are expressed as mean± standard deviation (SD). For statistical significance: ns, not significant;
p<0.05 and
p<0.001 between normal weight and obese groups. For abbreviations: HOMA-IR, homeostatic model of insulin resistance; TC, total cholesterol; LDL, low density lipoprotein; HDL, high density lipoprotein; FSH, follicle stimulating hormone; LH, luteinizing hormone; PRL, prolactin; E2, total estradiol.