Table 3.
Model |
Middle (≤ 63.29 yrs) |
Older (> 63.29 yrs) |
||||||
---|---|---|---|---|---|---|---|---|
Individual | Simultaneous | Individual | Simultaneous | |||||
Std. Est. | p | Std. Est. | p | Std. Est. | p | Std. Est. | p | |
TBV | 0.287 | <0.001 | – | – | 0.308 | <0.001 | – | – |
R2 | 0.082 | – | – | 0.095 | – | – | ||
GM | 0.276a | <0.001 | 0.159 | <0.001 | 0.328a | <0.001 | 0.298 | <0.001 |
NAWM | 0.257 | <0.001 | 0.134 | <0.001 | 0.268 | <0.001 | 0.054 | <0.001 |
WMH | −0.115a | <0.001 | −0.092 | <0.001 | −0.165a | <0.001 | −0.132 | 0.007 |
gFA | 0.113 | <0.001 | 0.051 | 0.029 | 0.108 | <0.001 | −0.096 | <0.001 |
gMD | −0.065 | 0.012 | 0.628 | −0.126 | −0.131 | <0.001 | ||
R2 | 0.054 | 0.136 |
Note. Std. Est: standardised estimate. Groups split at 63.29 years. aMagnitudes were significantly different by age, according to a χ2 test (FDR q < 0.05). Models are corrected for sex; brain measures also corrected for head positioning confounds. Associations between g and TBV were not significantly different between middle and older ages: Δχ2(1) = 3.874, p = .049, ΔAIC = 2, ΔsaBIC = −3.223. However, the magnitude of g associations with multiple global measures (simultaneously modelled) were significantly different between age groups: Δχ2(7) = 183.22, p ≤.001, ΔAIC = 169, ΔsaBIC = 134. TBV: total brain volume, GM: grey matter volume, WM: white matter volume, WMH: white matter hyperintensity volume, FA: fractional anisotropy, MD: mean diffusivity.