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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Tob Control. 2019 May 30;29(3):341–347. doi: 10.1136/tobaccocontrol-2018-054841

Ban on menthol-flavoured tobacco products predicts cigarette cessation at one year: a population cohort study

Michael Chaiton 1, Ioana Nicolau 1, Robert Schwartz 1, Joanna E Cohen 1, Eric Soule 1, Bo Zhang 1, Thomas Eissenberg 1
PMCID: PMC6884656  NIHMSID: NIHMS1037455  PMID: 31147474

Abstract

Objectives

The province of Ontario, Canada, banned the use of menthol-flavoured tobacco products as of January 1st, 2017. The long-term impact of a menthol ban on smoking behaviour has not been previously evaluated.

Methods:

Population cohort study with baseline survey conducted September-December 2016 and follow up January-August 2018 among residents of Ontario, Canada, 16 years old and over who reported current smoking (past 30 days) at baseline survey and completed follow up (n=913) including 187 reporting smoking menthol cigarettes daily, 420 reported smoking menthol cigarettes occasionally, and 306 were non-menthol cigarette smokers. Relative rates of making a quit attempt and being a non-smoker at follow up were estimated with Poisson regression controlling for smoking and demographic characteristics at baseline.

Results

At follow up, 63% of daily menthol smokers reported making a quit attempt since the ban compared to 62% of occasional menthol smokers and 43% of non-menthol smokers (adjusted relative rate (ARR) for daily menthol smokers compared to non-menthol smokers: 1.25; 95% CI 1.03-1.50). At follow up, 24% of daily menthol smokers reported making a quit since the ban compared to 20% of occasional menthol smokers and 14% of non-menthol smokers (ARR for daily menthol smokers compared to non-menthol smokers: 1.62; 95% CI 1.08, 2.42).

Conclusions

The study found a higher rates of quitting among daily and occasional menthol smokers in Ontario one year after the implementation of a menthol ban compared to non-menthol smokers.. Our findings suggest that restrictions on menthol may lead to substantial improvements in public health.

Keywords: Tobacco products, smoking cessation, public policy, menthol ban

INTRODUCTION

Menthol is a flavouring agent added to cigarettes that masks the taste of tobacco, induces sensory effects, and recruits and retains smokers.13 The Food and Drug Administration (FDA)4 the Tobacco Products Scientific Advisory Committee (TPSAC)5 and the World Health Organization (WHO)6 independently examined the evidence on the health rates of menthol cigarettes and produced separate reports. The FDA report concluded that “menthol cigarettes pose a public health rate above that seen with non-menthol cigarettes” and removing them from the market would be of public health benefit.4 The WHO made similar recommendations of “banning the use of menthol and its analogues, precursors or derivatives in cigarettes and possibly all tobacco products.”6

The FDA noted in their scientific evaluation that menthol has a physiological impact on smoking that increases initiation and progression to regular cigarette smoking, increases nicotine dependence and decreases smoking cessation success.4 These findings were consistent across three independent reports (TPSAC report, FDA report and a 2017 systematic review by Villanti et al.). 4,5,7 Further, the FDA report found that menthol smoking patterns differed by subpopulation.4 For instance, younger populations, females and black Americans were more likely to smoke menthol cigarettes.4 These menthol smoking patterns among subpopulations perfectly matched the targeted marketing strategies employed by the tobacco industry.4

Although there are strong recommendations for banning menthol tobacco products, very few countries have banned menthol cigarettes.8,9 Canada has implemented a new national ban to address rates of menthol cigarette use among youth.10 Other nations such as Brazil, Ethiopia Turkey and the European Union have passed regulations to ban menthol tobacco products.8.9 In the US, the Food and Drug Administration has announced intentions to regulate the sale of menthol in tobacco.11 San Francisco has already banned the sale of menthol cigarettes and other tobacco products with flavours and many other local and state jurisdiction have or are considering implementing restrictions.1214 Evaluating the impact of a menthol ban could inform the implementation of restrictions in other jurisdictions.

Several studies that have attempted to estimate the behavioural intentions following a menthol ban found that between 35% to 66% of current menthol smokers in the US stated they would quit if there was a menthol ban.1517 Further, a simulation study was conducted to predict the effects of a hypothetical menthol ban in the US on smoking prevalence and smoking-attributable deaths 40 years forward— to the year 2050.18 Data from the 2003 Tobacco Use Supplement to the Current Population Survey (TUS-CPS) were used and three plausible parameters or “scenarios” were considered for the proportion of smokers who would permanently quit after a hypothetical menthol ban and the proportion of individuals who would have initiated as menthol smokers but do not initiate as a result of the ban (i.e. 10%, 20% or 30%).18 The simulation study predicted that there would be between 4.8% and 9.7% relative reduction in smoking prevalence 40 years after a hypothetical menthol ban when compared with the prevalence in the absence of a menthol ban and between 323,000 and 633,000 smoking-attributable deaths could be avoided.18 The largest projected relative reduction was among black Americans (24.8%).18 Regardless of the scenario, a menthol ban was associated with a notable reduction in smoking-related deaths.18

The TPSAC menthol report (2011) also modelled the public health impact of a menthol ban 40 years forward to the year 2050 by comparing the status quo (i.e. US 2010 patterns of menthol and non-menthol smoking) to a counterfactual scenario without the availability of menthol cigarettes.5 Based on the TPSAC best estimates, there were an estimated 327,565 cumulative excess deaths by 2050 associated with the availability of menthol cigarettes. 5 Although the results from the Mendez modelling in the TPSAC report and Levy et al. were based on different models and assumptions, they both showed similar estimates of a 10% effect for the potential impact of a menthol ban.5,18

In Canada, menthol sales are less prevalent than in the US, accounting for only about 5% of the cigarette sale market, whereas in the US 35% of all cigarettes sold are mentholated.1921 Among Canadians age 15 and older in 2015, more than one-third (35.3%) of all respondents said they had ever smoked a menthol cigarette; 1.6% of all respondents had smoked one in the past 30 days.22 Similar to the US7, a considerable number of Canadian youth report smoking menthol cigarettes.10,21 According to the 2010-2011 Canadian Youth Smoking Survey, as many as 32% of current cigarette smokers used menthol cigarettes and in the 2012-2013 iteration almost 15% of students from grades 10–12 reported using flavoured tobacco (including menthol products).10

The concerns over the health effects of flavoured tobacco products led the Canadian government to limit flavoured tobacco but this legislation did not include mentholated products. However, on January 1, 2017, a year after the Canadian legislation on flavoured tobacco products, the province of Ontario implemented a ban on menthol-flavoured tobacco products. Shortly after the ban, a population-wide evaluation of smoking behaviour in Ontario was conducted.19 The study compared the planned behaviour of menthol smokers before the ban with their actual behaviour one-month post-ban and found that a greater percentage of menthol smokers attempted to quit after the ban than had planned before the ban.19 This suggests that the ban substantially increased quit attempts in the short duration after the ban, however, the long-term impact of the menthol ban is not known. It is uncertain what the long-term effects of the ban on smoking behaviour will be given that we have seen the tobacco industry change its tactics to prepare consumers for the menthol ban.23 Therefore, this study aims to estimate the effect of the menthol ban on smoking behaviours more than 1 year after the ban.

METHODS

Study sample

This study was based on a cohort of Ontario residents, ages 16 and over, who were current smokers at baseline (i.e. past month smokers) before the ban. Participants at baseline were recruited between September and December 2016, through random digit dialing of Ontario smokers (n=1026), plus a supplemental convenience sample of past year smokers (n=772). For the telephone sample, a simple single stage sampling design without stratification was used to randomly select Ontario residential telephone numbers from a commercial telephone list. The next birthday method was used to select the individual in the household over 16 who spoke English. Participation rate for the RDD rate was 44% with 6.7% refusal rate among known eligible participants. Smokers from the convenience sample were recruited through an email invitation. Participants were contacted at one year after the implementation of the menthol ban to complete an online survey. Participants who did not complete the online survey or did not have online access were interviewed by telephone. The online follow-up survey was conducted between January and August 2018 to examine smoking behaviour changes, with complete data on 913 participants. The subset of past year menthol smokers at baseline also completed a follow up survey January-March, 2017. An analysis comparing those with complete data compared to the baseline sample found that the complete sample varied by menthol status, education, and convenience or telephone sample (See Supplemental Appendix). This study was approved by the research ethics board of the University of Toronto, Ontario, Canada and participants gave consent to participate.

Measures

At baseline, participants reported past year use of menthol cigarettes as “every day”, “occasionally”, “on rare occasions”, or “not at all”. Menthol cigarette use was categorized into three categories: 1) “non-menthol users” defined as participants who had not used menthol cigarettes in the past year; 2) “daily menthol users” defined as people who used menthol cigarettes daily in the past year and were daily or almost daily users; and 3) “non-daily (occasional) menthol users” defined as people who used menthol occasionally or rarely in the past year. At the follow-up interview, participants reported their current use of menthol or non-menthol cigarettes (“every day”, “almost every day”, “occasionally”, “not at all”). An answer of “not at all” for menthol and non-menthol smoking was deemed to represent quitting smoking (outcome of interest). The secondary outcome was quit attempt, defined as self-reporting making a serious quit attempt since the beginning of the menthol cigarette ban in January 2017 (“Since January 1st 2017, have you made a serious attempt to quit smoking? By serious, we mean that you made a conscious attempt to stay off cigarettes for good”). All those who reported not smoking at follow were considered to have made a quit attempt. The use of e-cigarettes or cigars since the ban was assessed. Variables that were collected during the baseline survey included age, sex (male, female, other), education (“some elementary or some high school”, “completed high school”, “some community or technical college”, “completed community or technical college”, “some university”, “completed university”, refused), race (white, Asian, black, Latin American, Arab, Aboriginal, multiple cultural backgrounds, refused, other), the number of cigarettes smoked per day on days that they smoked.

Statistical analysis

Proportions with corresponding 95% confidence intervals (CIs) and the Pearson’s chi-square test were used to describe the study sample. Separate crude and adjusted Poisson regression models were performed for the primary outcome point prevalence “quit” and for the secondary outcome “quit attempt”. All Poisson regression were estimated with robust standard errors. Models were adjusted for baseline age, sex, education, race, as well as baseline number of cigarettes per day, baseline report of daily or non-daily smoking, use of e-cigarettes or cigars since the ban, survey source (i.e. RDD or convenience sample) and the number of days between the baseline and follow-up survey. Sensitivity analyses examined subpopulation estimates stratified by sex, age group (under the age of 30 and age 30 and above), race (white vs. non-white), daily vs. non-daily smoking, and time of follow up after implementation of the menthol ban (less than or equal to median time vs. more than median time). Likelihood ratio test was used to assess if an interaction term was statistically significant between models with and without the interaction term of the population subgroup and menthol status. The sensitivity of the outcome was examined by limiting the definition of quit to those who had not reported smoking within the past month and within the past six months. An additional sensitivity analyses was perfomed to account for missing data using an “intent to treat” approach whereby missing outcomes were coded as continued smokers. All analyses were performed using STATA Version 14.0 StataCorp LP.24

RESULTS

Of the 913 participants who completed both the baseline and one-year follow-up surveys, 306 (34%) were non-menthol cigarette smokers, 420 (46%) were occasional menthol smokers, and 187 (21%) were daily menthol cigarette smokers at baseline. More than half of the participants were female (58%), the majority of participants were over the age of 30 (84%) and white (83%), about 71% had more than a high school degree and about 39% smoked anywhere from 11 to 20 cigarettes a day with 10% being non-daily smokers. Overall, 19% of baseline smokers reported successfully quitting smoking and 56% reported making a quit attempt after the ban (Table 1). The three groups of participants – non-menthol smokers, occasional menthol smokers and daily menthol smokers – differed significantly by sex, age, education, race, and smoking behaviours (Table 1). Daily and occasional menthol smokers were more likely to be female, non white, and have more than a high school education than non-menthol smokers. Those who smoked menthol cigarettes occasionally had the highest percentage of young adults (i.e. between 16 and 29 years of age).

Table 1.

Characteristics of smokers, overall and by menthol use, in Ontario, Canada (N=913), 2016-2018

No menthol use Occasional menthol use Daily menthol use Total P-value
Characteristics n=306 (34%) n=420 (46%) n=187 (21%) N=913
% % % % n
Sex
 Female 50 60 65 58 527 0.017
 Male 49 40 34 42 380
 Other 1 1 1 1 6

Age
 16-29 4 24 16 16 143 p<0.001
 30 and over 96 76 84 84 770

Education
 ≤ High school 41 22 27 29 267 p<0.001
 > High school 59 78 73 71 646

Race
 Non-white 11 20 18 17 153 p=0.002
 White 89 80 82 83 760

Cigarettes per day
 0 to 10 32 37 35 35 318 p=0.012
 11 to 20 46 35 36 39 357
 21 to 30 14 17 13 15 139
 Over 30 7 11 16 11 99

Smoking Pattern
 Daily 95 82 100 90 824 p<0.001
 Non-Daily 5 18 0 10 89

Quit post-ban
 No 86 80 76 81 742 p=0.014
 Yes 14 20 24 19 171

Quit attempt post-ban
 No 57 38 37 44 400 p<0.001
 Yes 43 62 63 56 513

The median follow up time after the ban was 408 days with a range of 394 days to 595 days. At follow up, 0.3% of the non menthol smokers at baseline, 5% of the occasional menthol users, and 22% of the daily menthol users reported purchasing menthol cigarettes after the ban (p<0.001). the primary source for purchasing menthol cigarettes was on First Nations Reserves but this purchasing pattern did not increase over time among prior daily menthol smokers (short term follow up: 21%; long term follow up: 21%).

Menthol users, both daily and occasional, were more likely to report having quit smoking (24% and 20% vs. 14%; p=0.014) or having made a quit attempt (63% and 62% vs. 43%; p<0.001) than non-menthol smokers (Table 1). Of the 40 daily menthol users who reported being quit at the short term follow up (1–3 month post ban), 40% remained quit at the long term follow up, compared to 52% of the 227 occasional users who were quit at the short term follow up (non-menthol users at baseline did not have a short term follow up) (p=0.258). Daily menthol smokers reported an average of 1.9 quit attempts (0.42 SE) since the ban compared to 1.7 (0.17 SE) attempts among occasional menthol smokers and 1.0 attempts (0.12 SE) among the non-menthol smokers.

Of the 287 menthol smokers who predicted that they would switch to non-menthol cigarettes when surveyed prior to the ban, 15% reported being quit at the long term follow up. This compares to quit rates of 38% of those (n=60) among those who predicted that they would quit in response to the ban, 34% of those who predicted they would switch to other flavoured products, 19% (n=101) who predicted switching to contraband, and 24% of the 100 people who did not know their response (p<0.001).

Table 2 presents the crude and adjusted Poisson regression models for the association between post-ban self-reported smoking abstinence and having attempted to quit with menthol smoking at baseline (see details in Supplementary Appendix). Daily menthol smokers had significantly higher rate of reporting having quit smoking after the ban (adjusted rate ratio (ARR) 1.62; 95% confidence interval (CI) 1.08-2.42) compared to non-menthol smokers, controlling for smoking and demographic characteristics. After adjustment, the rate of occasional menthol smokers reporting having quit was 1.09 (95% CI 0.74-1.62) times higher than the rate of non-menthol smokers reporting having a quit. Unadjusted analysis displayed a significantly higher rate of reporting a quit attempt for daily and occasional menthol smokers compared to non-menthol smokers. In the adjusted analyses, only the daily menthol smokers were more likely to have tried to quit than non-menthol smokers (ARR 1.25; 95% CI 1.03-1.50). Stratified analyses are shown in Table 3 and Table 4 to show the variation in the population. Interactions between menthol status and subpopulations were not significant (data not shown) except for date of follow up (p=0.022) on the quit outcome and age (p=0.035) on the quit attempt outcome where the magnitude of the estimate was higher among those with short date of follow up and among those with older age, respectively.

Table 2.

Associations between menthol smoking status prior to menthol ban and post-ban quit attempt and quit in Ontario, Canada, using Poisson regression with robust variance estimation, 2016-2018. N=913

Quit Attempt Quit

Menthol use Crude RR (95% CI) Adjustedγ RR (95% CI) Crude RR (95% CI) Adjustedγ RR (95% CI)
No menthol 1.00 1.00 1.00 1.00
Occasional 1.44*** (1.24,1.66) 1.09 (0.92,1.30) 1.47* (1.05,2.07) 1.09 (0.74,1.62)
Daily use 1.45*** (1.23,1.72) 1.25* (1.03,1.50) 1.71** (1.17,2.51) 1.62* (1.08,2.42)

Rate ratio=RR; 95% Confidence interval=95% CI

γ

Analyses controlling for age, sex, race, education, survey source, cigarettes smoked per day, daily or non-daily smoking, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

*

p<0.05

**

p<0.01

***

p<0.001

Table 3.

Associations between menthol smoking status prior to menthol ban and post-ban quit in Ontario, Canada, using Poisson regression with robust variance estimation stratified by sex, age group, and race and daily/non daily smoking, 2016-2018


RR (95% CI)
Menthol use Females§

N=516
Males§

N=374
Age <30γ

N=140
Age ≥30γ

N=756
Non-white¥

N=148
White¥

N=748
Dailyα

N=807
Non-Dailyα
N=89
No menthol 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
Occasional 1.24 (0.73,2.09) 0.95 (0.51,1.77) 0.67 [0.24,1.83] 1.19 (0.79,1.80) 1.09 (0.32,3.74) 1.08 (0.72,1.63) 1.08 (0.70,1.65) 1.24 (0.46,3.29)
Daily use 1.55 (0.91,2.65) 1.6 (0.84,3.04) 1.34 (0.39,4.60) 1.62* (1.05,2.48) 2.03 (0.60,6.89) 1.55* (1.00,2.39) 1.62* (1.07,2.45)

Relative Rate=RR; 95% Confidence interval=95% CI

§

Analyses controlling for age, race, education, survey source, cigarettes smoked per day, daily or non-daily smoking, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

γ

Analyses controlling for age, sex, race, education, survey source, cigarettes smoked per day, daily or non-daily smoking, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

¥

Analyses controlling for age, sex, education, survey source, cigarettes smoked per day, daily or non-daily smoking, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

α

Analyses controlling for age, sex, race, education, survey source, cigarettes smoked per day, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

*

p<0.05

**

p<0.01

***

p<0.001

Table 4.

Associations between menthol smoking status prior to menthol ban and post-ban quit attempt in Ontario, Canada, using Poisson regression with robust variance estimation stratified by sex, age group, and race and daily/non daily smoking, 2016–2018

RR (95% CI)
Menthol use Females§
N=516
Males§
N=374
Age <30γ
N=140
Age ≥30γ
N=756
Non-white¥
N=148
White¥
N=748
Dailyα
N=807
Non-Dailyα
N=89
No menthol 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00
Occasional
1.16 (0.91,1.49)

1 (0.78,1.29)

0.65 (0.40,1.08)

1.15 (0.96,1.38)

0.87 (0.57,1.34)

1.13 (0.93,1.36)

1.13 (0.93,1.37)

0.92 (0.75,1.14)
Daily use 1.27 (0.98,1.65) 1.2 (0.91,1.57) 0.88 (0.48,1.61) 1.25* (1.03,1.53) 1.07 (0.67,1.72) 1.26* (1.03,1.55) 1.27* (1.04,1.54)

Relative Rate=RR; 95% Confidence interval=95% CI

§

Analyses controlling for age, race, education, survey source, cigarettes smoked per day, daily or non-daily smoking, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

γ

Analyses controlling for age, sex, race, education, survey source, cigarettes smoked per day, daily or non-daily smoking, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

¥

Analyses controlling for age, sex, education, survey source, cigarettes smoked per day, daily or non-daily smoking, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

α

Analyses controlling for age, sex, race, education, survey source, cigarettes smoked per day, use of cigars or e-cigarettes since the ban, and number of days between the menthol ban and the follow-up survey

*

p<0.05

**

p<0.01

***

p<0.001

In the sensitivity analyses (See Supplementary Appendix) including those who did not complete the one-year follow-up survey (N=1738), allowing all missing outcomes to represent continued smokers did not change the significance of our results nor did it greatly alter the magnitude of the estimates; daily menthol smokers had a relative rate of 2.34 (95% CI: 1.51, 3.62) of reporting quitting at follow up compared to non-menthol smokers (p<0.001), adjusted for age, sex, education, race, cigarettes per day, daily or occasional smoking, date of baseline survey and survey type. Using alternate, more stringent definitions of cessation did not change interpretation. One month (ARR:1.56; 95% CI: 1.04, 2.35) and six month self report cessation outcomes (ARR:1.61; 95% CI: 1.01, 2.55) both had similar magnitudes to point prevalence smoking comparing daily menthol smokers with non-menthol smokers. Similarly, limiting the sample to only those who had not purchased menthol cigarettes since the ban did not change interpretation (ARR: 2.39; 95% CI: 1.56, 3.65).

DISCUSSION

To our knowledge, this is the first long-term population-based pre-post evaluation of smoking behaviours after the implementation of a menthol-flavoured tobacco ban. Overall, the study found that there was a significantly higher rate of reported smoking cessation one year after the menthol ban for baseline daily menthol smokers when compared to non-menthol smokers. An association was also found between daily menthol cigarettes smokers and reports of quit attempts one-year post-ban compared to non-menthol smokers. Unadjusted effects for baseline occasional menthol smokers were attenuated after control for other demographic and baseline characteristics.

The results of this study support findings from previous studies conducted in the US of behavioural intentions and beliefs in the event of a menthol ban by the FDA.1114 In this study, behavioural intentions were correlated with quitting outcome—particularly those who felt that they would be satisfied with non-menthol cigarettes and those who expected to quit. Menthol smokers who intended to substitute with other means had substantial levels of quitting behaviour. In US studies, estimates of menthol smoker intention to quit smoking varied from 40%16 to 35%15, 30%18, with a 10% best estimate of effect from the TPSAC report.5 Our previous study evaluating short term quitting behaviour in Ontario one month after the ban found that 17% planned to quit long term.19 Although the demographics of menthol smokers in our study sample of Canadian smokers may not represent U.S. menthol smokers, our findings suggest that the effect of the menthol ban may be greater in countries where a greater number intend to quit because of the ban. In the current study we found that 20% of occasional menthol smokers and 24% of daily menthol smokers reported quitting in the long-term, which exceeded what was predicted by smokers at baseline. The quit rates reported by the non-menthol smokers are consistent with a previous population-representative longitudinal studies of quit rates in Ontario (8.9% sustained self reported quit rate).25 In Ontario, there were no public education campaigns to inform of the menthol ban, and the ban was implemented without noticeable controversy. Greater awareness of the ban, and greater support for cessation among menthol smokers may increase the effectiveness of the ban. However, the tobacco industry had promoted non-menthol cigarette brand alternatives to menthol smokers at point of sale.23

Twenty-two percent of daily menthol smokers reported purchasing menthol cigarettes after the ban, which is consistent with O’Connor and colleagues’ finding that 25% of menthol smokers claim that they would find some way to purchase menthol cigarettes despite a ban.15 Access to other provinces who had legal sales of menthol during a period of the ban in Ontario and close proximity to the United States did not appear to have significant impacts on availability. Access to sources from First Nations Reserves was high but did not appear to change over the course of the study.

The results from our study suggest that the ban on the sale of menthol tobacco products was associated with a higher level of quitting or attempting to quit smoking at 1-year follow-up among daily menthol smokers. In the US, where no national menthol ban has been implemented, cross-sectional studies showed that menthol users were less successful in quitting than non-menthol users despite increased quit attempts or intentions to quit.7 Considering that menthol smokers may be more nicotine dependent and have reduced cessation success,46 our findings that daily menthol smokers were significantly more likely to reporting smoking cessation relative to non-menthol smokers after the ban suggest that the menthol ban could have tremendous public health impact at the population level not only in Canada but in other jurisdictions as well from a overall reduced level of cigarette smoking.

This study has several strengths, namely it is a large population study with a long follow-up period. As with any cohort study, there is the potential issue of loss-to-follow-up. However, the sensitivity analysis using the intention to treat analysis led to similar results and did not change the conclusions of the study. While some of the study participants were recruited through random digit dialing, given the limitations of RDD, we do not expect that sample to be fully representative of the population. While representative samples can be valuable, understanding the effect in subpopulations as presented can be more helpful for generalizability to other jurisdictions outside of Ontario.26 While we found that self-reported quitting behaviour estimates did not differ statistically between subgroups, this may be due potentially due to sample size, despite previous studies showing effects.47 Another limitation of this study was using a point measurement self-reported measures of menthol use and quitting behaviour and the possibility that participants may not identify accurately the timing of activities that had occurred just before or after the implementation of the ban. However, there is no evidence that menthol smokers and non-menthol smokers would recall the quitting behaviour differently. Only menthol smokers were surveyed for short term smoking status, and the effect of quitting long term appeared to include the effect of initial short term quitting and lower levels of relapse among the daily menthol smokers compared to the occasional menthol smokers. Inclusion of objective biomarkers of cessation (e.g., expired air CO; saliva or urine cotinine concentration) would strengthen future studies.

Our findings suggest an increased rate of quitting one year following Ontario’s ban on the sale of menthol tobacco products. Although this impact was observed in older but not younger adults, the difference may be due to younger adults not having a brand preference and switching to other flavoured tobacco or nicotine products. Therefore, we would expect that a menthol ban would have an even greater impact in at-risk subpopulations such as youth and young adults in an environment in which there was less availability of any flavoured tobacco or nicotine products. Future work will need to examine the impact of all other flavoured products on long-term cessation.

Supplementary Material

Supplemental appendix

What is known:

Tobacco companies use menthol in cigarettes to increase smoking, reinforce addiction and discourage cessation. Existing studies have found reduced cessation among menthol cigarette smokers; it is unknown how a menthol cigarette ban would affect smoking cessation behavior.

What this paper adds:

Our study is a real-world assessment of the impact of a menthol cigarette ban. One year after the implementation of a menthol cigarette ban, daily menthol cigarette smokers were significantly more likely to report quit attempts and being quit compared to non-menthol cigarette smokers.

Acknowledgments

This research was supported by the National Institute on Drug Abuse (NIDA) of the U.S. National Institutes of Health (NIH) under Award Number P50DA036105 and the Center for Tobacco Products (CTP) of the U.S. Food and Drug Administration (FDA) and the NIH Office of the Director under award number 1R21DA047358-01. Dr. Eissenberg’s effort is also supported by NIDA and CTP/FDA under U54DA036105. The content is solely the responsibility of the authors and does not necessarily represent the views of the NIH or the FDA.

Footnotes

Conflicts of Interest: Dr. Eissenberg is a paid consultant in litigation against the tobacco industry and is named on a patent application for a device that measures the puffing behavior of electronic cigarette users.

Transparency Declaration The lead author affirms that the manuscript is an honest, accurate, and transparent account of the study being reported; that no important aspects of the study have been omitted; and that any discrepancies from the study as originally planned have been explained.

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