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. 2019 Nov 29;294(48):18518. doi: 10.1074/jbc.W119.011721

Withdrawal: Suppression of NF-κB survival signaling by nitrosylcobalamin sensitizes neoplasms to the anti-tumor effects of Apo2L/TRAIL.

Mamta Chawla-Sarkar, Joseph A Bauer, Joseph A Lupica, Bei H Morrison, Zhuo Tang, Rhonda K Oates, Alex Almasan, Joseph A DiDonato, Ernest C Borden, Daniel J Lindner
PMCID: PMC6885610  PMID: 31784479

VOLUME 278 (2003) PAGES 39461–39469

This article has been withdrawn by the authors (M. Chawla Sarkar, J. A. Bauer, J. A. Lupica, A. Almasan, J. A. DiDonato, and D. J. Lindner) on request by the Journal. B. H. Morrison, Z. Tang, R. K. Oates, and E. C. Borden could not be contacted. The Journal raised questions regarding inappropriate image manipulation in Figs. 4 (A and B) and 5B. Sixteen years after the publication, the withdrawing authors were not able to locate all of the original data but were able to locate some replicates of experiments performed at the time of the original work, which the withdrawing authors state support the conclusions of the paper. The withdrawing authors' offer to replace the images in question with alternative blots performed at the same time was declined by the Journal. The withdrawing authors state that the results of this paper are confirmed by the results of complementary experiments presented in the article and that the principal observations of this paper were further confirmed in the publications of other laboratories: 1) Huerta-Yepez, S. et al. (2004) Oncogene 23, 4993–5003; 2) Huerta-Yepez, S. et al. (2009) Nitric Oxide 20, 39–52; 3) Stupina, T. et al. (2018) Sci. Pharm. 86, E46; 4) Omar, H. A. et al. (2014) Basic Clin. Pharmacol. Toxicol. 114, 464–471. The withdrawing authors stand by the conclusions of the paper.


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