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. Author manuscript; available in PMC: 2019 Dec 3.
Published in final edited form as: Gut. 2016 Jan 4;66(4):724–735. doi: 10.1136/gutjnl-2015-310033

Figure 5. IFN-induced STAT1 and pSTAT expression in NK cells is greater during QUAD therapy than during PegIFN/RBV therapy.

Figure 5.

(A)Comparison of the decrease in HCV RNA levels during the first 24 h of therapy in 7 patients who were non-responders to a full course of PegIFN/RBV therapy but had an SVR during a subsequent course of QUAD therapy.

(B, C) Comparison of changes in the expression level of STAT1+ (B) and pSTAT1 (C) NK cells during the first 24 h of therapy in patients who were non-responders to a full course of PegIFN/RBV therapy but had an SVR during a subsequent course of QUAD therapy.

(D) Comparison of changes in the percentage of pSTAT1+ NK cells during the first 24 h of therapy in patients who were non-responders to a full course of PegIFN/RBV therapy but had an SVR during a subsequent course of QUAD therapy. Statistical analysis: non-parametric paired Wilcoxon-signed-rank test. Median and IQR are shown in the left graphs in panels A-D.