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. 2019 Nov 26;21(12):1151–1163. doi: 10.1016/j.neo.2019.08.005

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — The fictional link of CD151 to the phenotype of the luminal epithelial cell-derived mammary tumors. A Expression and distribution of E-cadherin, α 3 integrin and ER proteins in mammary tumors. B Analysis of expression of CD151-related adhesion molecules by immunoblotting. C: Recapturing of CD151-mediated cell interaction in breast cancer by the impact of its knockdown on the morphology of cultured MCF-10A cells in 2D (B) or 3D (C). C (a). Immunoblotting of Snail, Slug, Twist1 and KLF4 in mammary tumors. (b) IHC staining. D Image of human TNBC cells (HCC1937) with or without stable CD151 knockdown. Top panel, The-EMT-like change; bottom panel, confocal images of β -catenin staining in tumor cells. The specificity of CD151 shRNA was validated in a prior study [43]. Scale bar: 50 μm.

Fig. 4 — The fictional link of CD151 to the phenotype of the luminal epithelial cell-derived mammary tumors. A Expression and distribution of E-cadherin, α 3 integrin and ER proteins in mammary tumors. B Analysis of expression of CD151-related adhesion molecules by immunoblotting. C: Recapturing of CD151-mediated cell interaction in breast cancer by the impact of its knockdown on the morphology of cultured MCF-10A cells in 2D (B) or 3D (C). C (a). Immunoblotting of Snail, Slug, Twist1 and KLF4 in mammary tumors. (b) IHC staining. D Image of human TNBC cells (HCC1937) with or without stable CD151 knockdown. Top panel, The-EMT-like change; bottom panel, confocal images of β -catenin staining in tumor cells. The specificity of CD151 shRNA was validated in a prior study [43]. Scale bar: 50 μm.