Table 1.
General Structure | ||||||||
---|---|---|---|---|---|---|---|---|
Product | R1 | R2 | R3 | R4 | n | 8-HQ Derivative | Sugar Derivative | Yield [%] |
45 | Ac | OAc | H | H | 2 | 5 | 21 | 73 |
46 | Ac | H | OAc | H | 5 | 22 | 74 | |
47 | Ac | OAc | H | CH3 | 8 | 21 | 100 | |
48 | Ac | H | OAc | CH3 | 8 | 22 | 71 | |
49 | H | OH | H | H | 5 | 23 | 95 | |
50 | H | H | OH | H | 5 | 24 | 67 | |
51 | H | OH | H | CH3 | 8 | 23 | 88 | |
52 | H | H | OH | CH3 | 8 | 24 | 78 | |
53 | Ac | OAc | H | H | 3 | 6 | 21 | 100 |
54 | Ac | H | OAc | H | 6 | 22 | 100 | |
55 | Ac | OAc | H | CH3 | 9 | 21 | 65 | |
56 | Ac | H | OAc | CH3 | 9 | 22 | 77 | |
57 | H | OH | H | H | 6 | 23 | 100 | |
58 | H | H | OH | H | 6 | 24 | 76 | |
59 | H | OH | H | CH3 | 9 | 23 | 87 | |
60 | H | H | OH | CH3 | 9 | 24 | 65 | |
61 | Ac | OAc | H | H | 4 | 7 | 21 | 96 |
62 | Ac | H | OAc | H | 7 | 22 | 93 | |
63 | Ac | OAc | H | CH3 | 10 | 21 | 92 | |
64 | Ac | H | OAc | CH3 | 10 | 22 | 100 | |
65 | H | OH | H | H | 7 | 23 | 72 | |
66 | H | H | OH | H | 7 | 24 | 90 | |
67 | H | OH | H | CH3 | 10 | 23 | 76 | |
68 | H | H | OH | CH3 | 10 | 24 | 66 |