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. 2019 Jun 13;20(8):571–580. doi: 10.2217/pgs-2019-0020

Figure 2. . Pretreatment plasma estrone sulfate concentrations (pg/ml) stratified by SLCO1B1 genotype.

Figure 2. 

Concentrations below the LLOQ were censored at that value. Patients carrying SLCO1B1*5 (left) allele had significantly greater median E1S concentration (SLCO1B1*1/*1: n = 323, median = 222.0 pg/ml [interquartile range (IQR): 134.5–381.5]; SLCO1B1*1/*5: n = 108, median = 341.5 pg/ml [IQR: 208.75–533.75]; and SLCO1B1*5/*5, n = 7, median = 800.0 pg/ml [IQR: 324–975.5]). The opposite effect was seen for carrying rs10841753 (right) although the association was not as strong (SLCO1B1 wild-type T/T: n = 296, median = 285.5 pg/ml [IQR: 163.5–431.25]; SLCO1B1 heterozygous C/T: n = 130, median = 203.5 pg/ml [IQR: 114.75-387.0]; and SLCO1B1 homozygous variant C/C: n = 12, median = 238.0 pg/ml [IQR: 174.25–272.0]). In the box and whisker plot, the middle line represents the median, the box represents the IQR and the whiskers extend to 1.5 × IQR.

E1S: Estrone sulfate.