Table 3.
Plasma values at Pre-intervention, Week 24 and Week 28.
| Pre-intervention | Week 24 | Week 28 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| HF | HF+ | LF | LF+ | HF | HF+ | LF | LF+ | ||
| FFA (mmol/L) | 0.41 ± 0.04 | 0.64 ± 0.17 | 0.40 ± 0.10 | 0.63 ± 0.20 | 0.61 ±0.16 | 0.50 ± 0.21 | 0.42 ± 0.14 | 0.58 ± 0.20 | 0.42 ± 0.17 |
| ALP (U/L) | 46.13 ± 9.73 | 37.38 ± 7.76 | 40.0 ± 7.60 | 48.0 ± 9.32 | 47.25 ± 12.61 | 41.90 ± 8.36 | 38.5 ± 7.35 | 51.88 ± 10.66 | 50.13 ± 13.81 |
| LW (%) j | 4.15 (3.44–4.86) | 5.15 (4.58−5.72) | 4.82 (4.10−5.54) | 3.34 (2.91−3.77) f, h | 3.18 (2.73−3.63) f, i | 4.60 (3.64−5.56) | 5.96 (4.76−7.16) | 3.15 (2.81−3.50) e, i | 2.85 (2.53−3.16) b, f, i |
| BH2/BH4 | 0.05 ± 0.02 | 0.13 ± 0.037 c | 0.11 ± 0.03 a | 0.13 ± 0.03 c | 0.12 ± 0.04 b | 0.08 ± 0.04 | 0.10 ± 0.04 | 0.08 ± 0.03 | 0.07 ± 0.03 |
| TAA (µM) | 40.56 ± 17.09 | 37.39 ± 14.40 | 32.28 ± 12.93 | 70.73 ± 27.94 a, e, i | 57.64 ± 19.34 | 28.69 ± 6.92 | 33.85 ± 15.51 | 55.05 ± 11.11 d | 56.51 ± 10.56 d |
| αToc (µM) j | 4.52 (2.84−6.20) | 3.10 (1.91−4.29) | 6.70 (3.37−10.03) d | 1.35 (0.89−1.82) b, i | 1.89 (1.32−2.46) i | 2.70 (1.73−3.68) | 6.63 (2.88−10.38) d | 1.59 (0.94−2.23) a, h | 2.69 (1.62−3.77) g |
FFA, free fatty acid; ALP, alkaline phosphatase; LW, liver weight; BH2/BH4, dihydrobiopterin/tetrahydrobiopterin ratio; AA, ascorbic acid; DHA, dehydroascorbate; α-Toc, alpha-tocopherol. Data are presented as mean ± standard deviation.j Data are presented as geometric mean with 95 confidence intervals. a p < 0.05, b p < 0.01, c p < 0.001, compared with preintervention.d p < 0.05, e p < 0.01, f p < 0.001, compared with HF.g p < 0.05 h p < 0.01, i p < 0.001, compared with HF+.