FIGURE 4:

Temperature dependence of the preexponential α_i and τ_i for triexponential fits for wild-type (top) and mutant (bottom) proteins. Long lifetime (●), medium lifetime (▲), and short lifetime (■) are given. In the lifetime profiles (right), the dashed lines are the temperature-dependence profiles from the global Arrhenius analysis (see Discussion). For the wild-type, these dashed lines are for E_a,1 = 1.0 kcal/mol and A₁ = 0.987 ns⁻¹ for τ₁; E_a,2 = 1.76 kcal/mol and A₂ = 8.54 ns⁻¹ for τ₂; and E_a,3 = 4.0 kcal/mol and A₃ = 1901 ns⁻¹ for τ₃.