We read the publication on “Zika virus infection followed by a first episode of psychosis” with great interest.1 Corrêa-Oliveira et al. noted that “to the best of our knowledge, this is the first report in which psychiatric symptoms were the only complication of acute ZIKV infection”1 and concluded that “Neuroimmune mechanisms leading to psychosis during acute CNS stress is an open and prolific field for research.”1 In fact, a wide clinical spectrum of Zika virus infection has been reported, and psychological problems are possible.2,3 Neuropsychiatric problems as the only clinical presentation in acute Zika virus disease is not a new finding. At least, psychotic features in acute Zika virus infection have already been observed in cases in which meningoencephalitis was later proved.4 In the Zika virus infection with meningoencephalitis, spatial delusions with visual and kinesthetic hallucinations are observable.5
Disclosure
The authors report no conflicts of interest.
References
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