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. 2019 May 11;35(23):5011–5017. doi: 10.1093/bioinformatics/btz357

Fig. 3.

Fig. 3.

False positives. This figure shows the number of FPs obtained with different sample size n. The number of FPs are shown in Panels (a) and (b) under H0: no partial correlation (i.e. the percentages of true correlations δ is zero). Inference is carried out from simulated data for p = 100 and n ranging from 10 to 150 in steps of size 10. The black horizontal line represents the expected number of FPs under H0, tested at α = 0.05 and 0.01 respectively (i.e. 247.5 for α = 0.05 and 49.5 for α=0.01). Panels (c) and (d) show the number of FPs for different proportions p/n when the percentages of non-zero correlations is δ = 0.01. Here p = 50, 100, 150, 200 and n  = 20. Three approaches are compared: ENF (dot with dashed line), Shrunk MLE (square with dotted line), and MC with 15 iterations (triangle with continuous line). Symbols (and bars) represent the average (±2 SE) over 25 repeated simulations. The upper horizontal axis shows the average shrinkage intensity λ rounded to two digits