Table 3.
Association between rs841, A930G p22phox, rs1799983 genotypes and the severity of OSA.
| SNP | Genotype | Non-severe | Severe | Crude OR | P value | Adjusted OR | P value |
|---|---|---|---|---|---|---|---|
| N = 51 | N = 43 | (95% CI) | |||||
| Rs841 | GG | 26 | 33 | 1.00 (Reference) | |||
| GA | 23 | 9 | 0.3 (0.12–0.78) | 0.01 | 0.21 (0.07–0.62) | 0.005 | |
| AA | 2 | 1 | 0.3 (0.02–3.58) | 0.44 | 0.05 (0.002–1.32) | 0.07 | |
| A930G p22phox | GG | 14 | 13 | 1.00 (Reference) | |||
| GA | 31 | 22 | 0.76 (0.3–1.92) | 0.57 | 0.61 (0.22–1.7) | 0.35 | |
| AA | 6 | 8 | 1.43 (0.38–4.7) | 0.58 | 1.14 (0.27–4.84) | 0.85 | |
| Rs1799983 | GG | 28 | 23 | 1.00 (Reference) | |||
| GT | 18 | 19 | 1.28 (0.55–3.03) | 0.56 | 0.92 (0.36–2.31) | 0.86 | |
| TT | 5 | 1 | 0.24 (0.01–2.11) | 0.18 | 0.33 (0.33–3.36) | 0.35 |
SNP: Single Nucleotide Polymorphism, OSA: Obstructive Sleep Apnea, OR: Odd Ratio, CI: Confidence Interval. Adjusted odds ratio were adjusted for age, gender and body mass index.