We thank the author1 for her interest in our study2.
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(i)
The authors have mentioned about the definition of a pandrug-resistant (PDR) isolate as described by Ghafur et al3. This implies that the criteria have been followed to brand the organism as a PDR.
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(ii)
It is agreed that the CLSI/EUCAST-approved micro broth dilution remains a challenge till date in routine microbiology laboratories. Hence, this is not being used in our laboratory which is a routine laboratory only. Instead, the available and accessible methods are used. Hence, susceptibility to colistin has been determined by E-strip as well as correlating it with VITEK-2 minimum inhibitory concentration reports. We are aware that both these methods can have major errors. Therefore, it has been stated that colistin susceptibility has to be interpreted with caution and treatment should be done only after judicious clinical assessment. The isolates were judged as pathogen or colonizer by two independent assessors before being actually treated.
Footnotes
Conflicts of Interest: None.
References
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