Fig. 5.

From the Maestro study using the Seno Imagio linear system: a grade II invasive ductal carcinoma that was upgraded from PA/US findings. (A) Photoacoustic US shows findings similar to those from conventional US leading to BI-RADS 4A classification. (B) PA/US shows multiple internal vasculature including deoxygenated (red) vessels with intense deoxygenated anterior boundary zone blush (arrowheads) and boundary zone neovessels (arrows). (C) PA/US total hemoglobin map shows markedly increased hemoglobin within the central tumor. The mass was upgraded from BI-RADS 4A from gray-scale US and US Doppler, to BI-RADS 4C from PA/US. (Reproduced with permission of the authors and publisher.)