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. 2019 Nov 5;8(11):1395. doi: 10.3390/cells8111395

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Invadopodia-related gene expression correlates with the aggressiveness of HCV-mediated HCC and poor patient prognosis. Cluster gram of overexpressed invadopodia-associated genes by hazard ratio (HR). Columns represent HR values of OS (overall survival) and DFS (disease-free survival) in HCC patients (n = 377) and HCV-related HCC (n = 47). Genes are clustered in groups where the upper clusters are associated with the worst survival in HCV-related HCC. qRT-PCR validated genes are marked by an asterisk (*), and EGFR, TC-PTP (PTPN2), HB-EGF, and BTC are marked by two asterisks (**).