Skip to main content
. 2019 Nov 12;8(11):1422. doi: 10.3390/cells8111422

Figure 3.

Figure 3

Early oligodendrocyte progenitor cells (OPC) differentiation after 14 days of multifactor treatment. (a) Heatmap showing the percent of area positive for platelet-derived growth factor alpha (PDGFRa), as a measure for early OPC differentiation, dependent on the platelet-derived growth factor subunit A dimer (PDGF–AA) and fibroblast growth factor 2 (FGF2) treatment. (b) Representative microscopy images showing the PDGFRa expression upon different PDGF–AA and FGF2 treatments. (c) Heatmap showing the PDGFRa expression in dependency of the PDGF–AA/FGF2 and bone morphogenetic protein 2 (BMP2) treatment. (d) Representative microscopy images of PDGF–AA and FGF2 concentrated at 20 ng/mL and with BMP2 levels of 0–100 ng/mL. (e) Heatmap showing the PDGFRa expression in dependency of the PDGF–AA/FGF2 and BMP4 treatment. (f) Representative microscopy images of PDGF and FGF2 concentrated at 20 ng/mL and with BMP4 levels of 0–100 ng/mL.