Table 1.

Summary of animal and human models listed in Section 4.1 and Section 4.2. This list provides examples of a variety of models available to study OPC and oligodendrocyte (OL) biology.

In vitro Animal Models	In vitro Human Models	In Vivo Animal Models
OPC/OL cultures [128,129,130]	OPC derived from biopsies [138] or post mortem CNS [139]	Reporter mice (e.g., Sox10-Venus mice, CNP-EGFP mice, PLP-EGFP mice) [147,148,149]
Immortalized oligodendroglial cells lines (e.g., CG-4, OLN-93, Oli-neu) [133,134,135]	iOL derived from human iPSC [137,141,142,143]	Reporter zebrafish (e.g., Tg(sox10:mRFP), Tg(olig2:EGFP), Tg(mbp:EGFP)) [103,150,151]

OPC: Oligodendrocyte Progenitor Cell, OL: oligodendrocyte, CNS: Central Nervous System, iOL: induced Oligodendrocyte, iPSC: induced Pluripotent Stem Cell.