The authors regret of a mistake in submitting the incorrect Fig. 4A figure images, which should have been replaced with the newly-inserted, correct Fig. 4A images.
Fig. 4.
Urolithin A and Ellagic acid suppressed the CYP2E1 amount, oxidative stress and inflammation maker proteins in alcohol-exposed AML12 liver cells. AML12 liver cells were treated with culture media (CON) or 100 mM ethanol (EtOH) in the absence or presence of 15 µM Urolithin A (UA), 100 µM Ellagic acid (EA), or 15 µM chlormethiazole (CMZ) for 24 h, as indicated. (A) Confocal image showing the reduction of CYP2E1 in ethanol-exposed AML12 cells with or without UA, EA, or the CYP2E1 inhibitor CMZ. Cell nuclei were counter-stained with DAPI. (B) Immunoblot analyses for CYP2E1, iNOS, and nitrated proteins detected by anti-3-NT antibody in AML12 cell lysates for the indicated groups. Densitometric quantitation of the immunoblots for each protein, relative to the loading control β-actin, is shown where each lane represents the protein samples equally combined from 2 specimens within the same groups (n=4/group). (C) The levels of mRNA transcripts for NLRP3, IL-1β, and TNF-α in the indicated groups are presented (n=4/group). Significant difference between various treatments was determined by one-way ANOVA. Labeled characters without a common letter represent significant differences from the other group(s).
The authors would like to apologize for any inconvenience caused.