In the original article, there was a mistake in Figure 6D as published. The ordinate was not corrected for liquid junction potential. The corrected Figure 6 appears below.
Figure 6.
Ribbon-to-ribbon Ca2+ activation is more variable than cone-to-cone ICa activation. (A) ICa in one cone with Rser completely compensated. ICa was normalized to its peak value and plotted against the cone holding potential during the voltage ramp protocol (gray trace). A Boltzmann function adjusted for driving force was fit to these data (black line, V50 = −39.3, slope factor = 4.88). Inward currents are plotted upward to compare more easily with Ca2+ signal measurements. For this illustration, currents were digitally corrected for the passive membrane resistance measured in the range from −85 mV to −70 mV. (B) Overlaid Boltzmann function fits to normalized ICa from the 28 cones in which ribbon Ca2+ signals in Panel (C) were measured. (C) Overlaid Boltzmann function fits to ribbon-associated Ca2+ signals of 47 ribbons in the 28 cones shown in Panel (B). Ribbons were analyzed as illustrated in Figure 1. (D) Distribution of V50 values calculated from Boltzmann function fits to ICa (average = −38.1 ± 3.0 mV) and optical ribbon Ca2+ measurements made with OGB-5N (average = −34.8 ± 3.5 mV). Bars show the mean ± SD.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.